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Regulation of skeletal muscle growth by the IGF1-Akt/PKB pathway: insights from genetic models
A highly conserved signaling pathway involving insulin-like growth factor 1 (IGF1), and a cascade of intracellular components that mediate its effects, plays a major role in the regulation of skeletal muscle growth. A central component in this cascade is the kinase Akt, also called protein kinase B...
Autores principales: | Schiaffino, Stefano, Mammucari, Cristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143906/ https://www.ncbi.nlm.nih.gov/pubmed/21798082 http://dx.doi.org/10.1186/2044-5040-1-4 |
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