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Irinotecan induces steroid and xenobiotic receptor (SXR) signaling to detoxification pathway in colon cancer cells

BACKGROUND: Resistance to chemotherapy remains one of the principle obstacles to the treatment of colon cancer. In order to identify the molecular mechanism of this resistance, we investigated the role of the steroid and xenobiotic receptor (SXR) in the induction of drug resistance. Indeed, this nuc...

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Detalles Bibliográficos
Autores principales:	Basseville, Agnes, Preisser, Laurence, de Carné Trécesson, Sophie, Boisdron-Celle, Michèle, Gamelin, Erick, Coqueret, Olivier, Morel, Alain
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144021/ https://www.ncbi.nlm.nih.gov/pubmed/21733184 http://dx.doi.org/10.1186/1476-4598-10-80

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