17β-Estradiol Enhances Breast Cancer Cell Motility and Invasion via Extra-Nuclear Activation of Actin-Binding Protein Ezrin

Estrogen promotes breast cancer metastasis. However, the detailed mechanism remains largely unknown. The actin binding protein ezrin is a key component in tumor metastasis and its over-expression is positively correlated to the poor outcome of breast cancer. In this study, we investigate the effects...

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Detalles Bibliográficos
Autores principales: Zheng, Shuhui, Huang, Jinghe, Zhou, Kewen, Zhang, Chengxi, Xiang, Qiuling, Tan, Zhi, Wang, Tinghuai, Fu, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144228/
https://www.ncbi.nlm.nih.gov/pubmed/21818323
http://dx.doi.org/10.1371/journal.pone.0022439

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