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The diagnosis and management of pre-invasive breast disease: Pathology of atypical lobular hyperplasia and lobular carcinoma in situ
The term lobular neoplasia refers to a spectrum of lesions featuring atypical lobular hyperplasia and lobular carcinoma in situ (LCIS). The histopathological characteristics of these lesions are well documented. What is less well understood is the management implications of a patient diagnosed with...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC314428/ https://www.ncbi.nlm.nih.gov/pubmed/12927036 |
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author | Simpson, Peter T Gale, Theodora Fulford, Laura G Reis-Filho, Jorge S Lakhani, Sunil R |
author_facet | Simpson, Peter T Gale, Theodora Fulford, Laura G Reis-Filho, Jorge S Lakhani, Sunil R |
author_sort | Simpson, Peter T |
collection | PubMed |
description | The term lobular neoplasia refers to a spectrum of lesions featuring atypical lobular hyperplasia and lobular carcinoma in situ (LCIS). The histopathological characteristics of these lesions are well documented. What is less well understood is the management implications of a patient diagnosed with LCIS; treatment regimes vary and are somewhat controversial. LCIS is now considered a risk factor and a non-obligate precursor for the subsequent development of invasive cancer. |
format | Text |
id | pubmed-314428 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2003 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-3144282004-01-17 The diagnosis and management of pre-invasive breast disease: Pathology of atypical lobular hyperplasia and lobular carcinoma in situ Simpson, Peter T Gale, Theodora Fulford, Laura G Reis-Filho, Jorge S Lakhani, Sunil R Breast Cancer Res Review The term lobular neoplasia refers to a spectrum of lesions featuring atypical lobular hyperplasia and lobular carcinoma in situ (LCIS). The histopathological characteristics of these lesions are well documented. What is less well understood is the management implications of a patient diagnosed with LCIS; treatment regimes vary and are somewhat controversial. LCIS is now considered a risk factor and a non-obligate precursor for the subsequent development of invasive cancer. BioMed Central 2003 2003-07-29 /pmc/articles/PMC314428/ /pubmed/12927036 Text en Copyright © 2003 BioMed Central Ltd |
spellingShingle | Review Simpson, Peter T Gale, Theodora Fulford, Laura G Reis-Filho, Jorge S Lakhani, Sunil R The diagnosis and management of pre-invasive breast disease: Pathology of atypical lobular hyperplasia and lobular carcinoma in situ |
title | The diagnosis and management of pre-invasive breast disease: Pathology of atypical lobular hyperplasia and lobular carcinoma in situ |
title_full | The diagnosis and management of pre-invasive breast disease: Pathology of atypical lobular hyperplasia and lobular carcinoma in situ |
title_fullStr | The diagnosis and management of pre-invasive breast disease: Pathology of atypical lobular hyperplasia and lobular carcinoma in situ |
title_full_unstemmed | The diagnosis and management of pre-invasive breast disease: Pathology of atypical lobular hyperplasia and lobular carcinoma in situ |
title_short | The diagnosis and management of pre-invasive breast disease: Pathology of atypical lobular hyperplasia and lobular carcinoma in situ |
title_sort | diagnosis and management of pre-invasive breast disease: pathology of atypical lobular hyperplasia and lobular carcinoma in situ |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC314428/ https://www.ncbi.nlm.nih.gov/pubmed/12927036 |
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