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The diagnosis and management of pre-invasive breast disease: Pathology of atypical lobular hyperplasia and lobular carcinoma in situ

The term lobular neoplasia refers to a spectrum of lesions featuring atypical lobular hyperplasia and lobular carcinoma in situ (LCIS). The histopathological characteristics of these lesions are well documented. What is less well understood is the management implications of a patient diagnosed with...

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Autores principales: Simpson, Peter T, Gale, Theodora, Fulford, Laura G, Reis-Filho, Jorge S, Lakhani, Sunil R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC314428/
https://www.ncbi.nlm.nih.gov/pubmed/12927036
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author Simpson, Peter T
Gale, Theodora
Fulford, Laura G
Reis-Filho, Jorge S
Lakhani, Sunil R
author_facet Simpson, Peter T
Gale, Theodora
Fulford, Laura G
Reis-Filho, Jorge S
Lakhani, Sunil R
author_sort Simpson, Peter T
collection PubMed
description The term lobular neoplasia refers to a spectrum of lesions featuring atypical lobular hyperplasia and lobular carcinoma in situ (LCIS). The histopathological characteristics of these lesions are well documented. What is less well understood is the management implications of a patient diagnosed with LCIS; treatment regimes vary and are somewhat controversial. LCIS is now considered a risk factor and a non-obligate precursor for the subsequent development of invasive cancer.
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spelling pubmed-3144282004-01-17 The diagnosis and management of pre-invasive breast disease: Pathology of atypical lobular hyperplasia and lobular carcinoma in situ Simpson, Peter T Gale, Theodora Fulford, Laura G Reis-Filho, Jorge S Lakhani, Sunil R Breast Cancer Res Review The term lobular neoplasia refers to a spectrum of lesions featuring atypical lobular hyperplasia and lobular carcinoma in situ (LCIS). The histopathological characteristics of these lesions are well documented. What is less well understood is the management implications of a patient diagnosed with LCIS; treatment regimes vary and are somewhat controversial. LCIS is now considered a risk factor and a non-obligate precursor for the subsequent development of invasive cancer. BioMed Central 2003 2003-07-29 /pmc/articles/PMC314428/ /pubmed/12927036 Text en Copyright © 2003 BioMed Central Ltd
spellingShingle Review
Simpson, Peter T
Gale, Theodora
Fulford, Laura G
Reis-Filho, Jorge S
Lakhani, Sunil R
The diagnosis and management of pre-invasive breast disease: Pathology of atypical lobular hyperplasia and lobular carcinoma in situ
title The diagnosis and management of pre-invasive breast disease: Pathology of atypical lobular hyperplasia and lobular carcinoma in situ
title_full The diagnosis and management of pre-invasive breast disease: Pathology of atypical lobular hyperplasia and lobular carcinoma in situ
title_fullStr The diagnosis and management of pre-invasive breast disease: Pathology of atypical lobular hyperplasia and lobular carcinoma in situ
title_full_unstemmed The diagnosis and management of pre-invasive breast disease: Pathology of atypical lobular hyperplasia and lobular carcinoma in situ
title_short The diagnosis and management of pre-invasive breast disease: Pathology of atypical lobular hyperplasia and lobular carcinoma in situ
title_sort diagnosis and management of pre-invasive breast disease: pathology of atypical lobular hyperplasia and lobular carcinoma in situ
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC314428/
https://www.ncbi.nlm.nih.gov/pubmed/12927036
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