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The diagnosis and management of pre-invasive breast disease: Pathological diagnosis – problems with existing classifications
In this review, we comment on the reasons for disagreement in the concepts, diagnosis and classifications of pre-invasive intraductal proliferations. In view of these disagreements, our proposal is to distinguish epithelial hyperplasia, lobular carcinoma in situ and ductal carcinoma in situ, and to...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC314433/ https://www.ncbi.nlm.nih.gov/pubmed/12927038 |
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author | Van de Vijver, Marc J Peterse, Hans |
author_facet | Van de Vijver, Marc J Peterse, Hans |
author_sort | Van de Vijver, Marc J |
collection | PubMed |
description | In this review, we comment on the reasons for disagreement in the concepts, diagnosis and classifications of pre-invasive intraductal proliferations. In view of these disagreements, our proposal is to distinguish epithelial hyperplasia, lobular carcinoma in situ and ductal carcinoma in situ, and to abandon the use of poorly reproducible categories, such as atypical ductal hyperplasia or ductal intraepithelial neoplasia, followed by a number to indicate the degree of proliferation and atypia, as these are not practical for clinical decision making, nor for studies aimed at improving the understanding of breast cancer development. If there is doubt about the classification of an intraductal proliferation, a differential diagnosis and the reason for and degree of uncertainty should be given, rather than categorizing a proliferation as atypical. |
format | Text |
id | pubmed-314433 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2003 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-3144332004-01-17 The diagnosis and management of pre-invasive breast disease: Pathological diagnosis – problems with existing classifications Van de Vijver, Marc J Peterse, Hans Breast Cancer Res Review In this review, we comment on the reasons for disagreement in the concepts, diagnosis and classifications of pre-invasive intraductal proliferations. In view of these disagreements, our proposal is to distinguish epithelial hyperplasia, lobular carcinoma in situ and ductal carcinoma in situ, and to abandon the use of poorly reproducible categories, such as atypical ductal hyperplasia or ductal intraepithelial neoplasia, followed by a number to indicate the degree of proliferation and atypia, as these are not practical for clinical decision making, nor for studies aimed at improving the understanding of breast cancer development. If there is doubt about the classification of an intraductal proliferation, a differential diagnosis and the reason for and degree of uncertainty should be given, rather than categorizing a proliferation as atypical. BioMed Central 2003 2003-07-29 /pmc/articles/PMC314433/ /pubmed/12927038 Text en Copyright © 2003 BioMed Central Ltd |
spellingShingle | Review Van de Vijver, Marc J Peterse, Hans The diagnosis and management of pre-invasive breast disease: Pathological diagnosis – problems with existing classifications |
title | The diagnosis and management of pre-invasive breast disease: Pathological diagnosis – problems with existing classifications |
title_full | The diagnosis and management of pre-invasive breast disease: Pathological diagnosis – problems with existing classifications |
title_fullStr | The diagnosis and management of pre-invasive breast disease: Pathological diagnosis – problems with existing classifications |
title_full_unstemmed | The diagnosis and management of pre-invasive breast disease: Pathological diagnosis – problems with existing classifications |
title_short | The diagnosis and management of pre-invasive breast disease: Pathological diagnosis – problems with existing classifications |
title_sort | diagnosis and management of pre-invasive breast disease: pathological diagnosis – problems with existing classifications |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC314433/ https://www.ncbi.nlm.nih.gov/pubmed/12927038 |
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