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The diagnosis and management of pre-invasive breast disease: Pathological diagnosis – problems with existing classifications

In this review, we comment on the reasons for disagreement in the concepts, diagnosis and classifications of pre-invasive intraductal proliferations. In view of these disagreements, our proposal is to distinguish epithelial hyperplasia, lobular carcinoma in situ and ductal carcinoma in situ, and to...

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Detalles Bibliográficos
Autores principales: Van de Vijver, Marc J, Peterse, Hans
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC314433/
https://www.ncbi.nlm.nih.gov/pubmed/12927038
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author Van de Vijver, Marc J
Peterse, Hans
author_facet Van de Vijver, Marc J
Peterse, Hans
author_sort Van de Vijver, Marc J
collection PubMed
description In this review, we comment on the reasons for disagreement in the concepts, diagnosis and classifications of pre-invasive intraductal proliferations. In view of these disagreements, our proposal is to distinguish epithelial hyperplasia, lobular carcinoma in situ and ductal carcinoma in situ, and to abandon the use of poorly reproducible categories, such as atypical ductal hyperplasia or ductal intraepithelial neoplasia, followed by a number to indicate the degree of proliferation and atypia, as these are not practical for clinical decision making, nor for studies aimed at improving the understanding of breast cancer development. If there is doubt about the classification of an intraductal proliferation, a differential diagnosis and the reason for and degree of uncertainty should be given, rather than categorizing a proliferation as atypical.
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spelling pubmed-3144332004-01-17 The diagnosis and management of pre-invasive breast disease: Pathological diagnosis – problems with existing classifications Van de Vijver, Marc J Peterse, Hans Breast Cancer Res Review In this review, we comment on the reasons for disagreement in the concepts, diagnosis and classifications of pre-invasive intraductal proliferations. In view of these disagreements, our proposal is to distinguish epithelial hyperplasia, lobular carcinoma in situ and ductal carcinoma in situ, and to abandon the use of poorly reproducible categories, such as atypical ductal hyperplasia or ductal intraepithelial neoplasia, followed by a number to indicate the degree of proliferation and atypia, as these are not practical for clinical decision making, nor for studies aimed at improving the understanding of breast cancer development. If there is doubt about the classification of an intraductal proliferation, a differential diagnosis and the reason for and degree of uncertainty should be given, rather than categorizing a proliferation as atypical. BioMed Central 2003 2003-07-29 /pmc/articles/PMC314433/ /pubmed/12927038 Text en Copyright © 2003 BioMed Central Ltd
spellingShingle Review
Van de Vijver, Marc J
Peterse, Hans
The diagnosis and management of pre-invasive breast disease: Pathological diagnosis – problems with existing classifications
title The diagnosis and management of pre-invasive breast disease: Pathological diagnosis – problems with existing classifications
title_full The diagnosis and management of pre-invasive breast disease: Pathological diagnosis – problems with existing classifications
title_fullStr The diagnosis and management of pre-invasive breast disease: Pathological diagnosis – problems with existing classifications
title_full_unstemmed The diagnosis and management of pre-invasive breast disease: Pathological diagnosis – problems with existing classifications
title_short The diagnosis and management of pre-invasive breast disease: Pathological diagnosis – problems with existing classifications
title_sort diagnosis and management of pre-invasive breast disease: pathological diagnosis – problems with existing classifications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC314433/
https://www.ncbi.nlm.nih.gov/pubmed/12927038
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