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HJURP is a CENP-A chromatin assembly factor sufficient to form a functional de novo kinetochore

Centromeres of higher eukaryotes are epigenetically marked by the centromere-specific CENP-A nucleosome. New CENP-A recruitment requires the CENP-A histone chaperone HJURP. In this paper, we show that a LacI (Lac repressor) fusion of HJURP drove the stable recruitment of CENP-A to a LacO (Lac operon...

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Detalles Bibliográficos
Autores principales:	Barnhart, Meghan C., Kuich, P. Henning J. L., Stellfox, Madison E., Ward, Jared A., Bassett, Emily A., Black, Ben E., Foltz, Daniel R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2011
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144403/ https://www.ncbi.nlm.nih.gov/pubmed/21768289 http://dx.doi.org/10.1083/jcb.201012017

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