Comparative analysis of the ATRX promoter and 5' regulatory region reveals conserved regulatory elements which are linked to roles in neurodevelopment, alpha-globin regulation and testicular function

BACKGROUND: ATRX is a tightly-regulated multifunctional protein with crucial roles in mammalian development. Mutations in the ATRX gene cause ATR-X syndrome, an X-linked recessive developmental disorder resulting in severe mental retardation and mild alpha-thalassemia with facial, skeletal and genit...

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Detalles Bibliográficos
Autores principales: Tang, Paisu, Frankenberg, Stephen, Argentaro, Anthony, Graves, Jennifer M, Familari, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144453/
https://www.ncbi.nlm.nih.gov/pubmed/21676266
http://dx.doi.org/10.1186/1756-0500-4-200

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