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Paraganglioma of the cauda equina region: A report of three cases

BACKGROUND: Cauda equina paragangliomas (CEP) are rare tumors. Low back pain and sciatica are the main presenting symptoms. Magnetic resonance imaging (MRI) is the study of choice and treatment consists of total excision when feasible. Definitive diagnosis can only be made after immunohistochemical...

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Autores principales: Ardon, Hilko, Plets, Christiaan, Sciot, Raf, Calenbergh, Frank Van
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144596/
https://www.ncbi.nlm.nih.gov/pubmed/21811702
http://dx.doi.org/10.4103/2152-7806.82989
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author Ardon, Hilko
Plets, Christiaan
Sciot, Raf
Calenbergh, Frank Van
author_facet Ardon, Hilko
Plets, Christiaan
Sciot, Raf
Calenbergh, Frank Van
author_sort Ardon, Hilko
collection PubMed
description BACKGROUND: Cauda equina paragangliomas (CEP) are rare tumors. Low back pain and sciatica are the main presenting symptoms. Magnetic resonance imaging (MRI) is the study of choice and treatment consists of total excision when feasible. Definitive diagnosis can only be made after immunohistochemical investigation. CEP is classified as grade I WHO and after total removal the prognosis is excellent. Nonetheless, after subtotal removal, tumor recurrence can occur. CASE DESCRIPTION: We present 3 cases of CEP, preoperatively diagnosed as an intradural mass on MRI and suspected to be ependymoma. All 3 patients presented with low back pain and variable sciatic pain. Total resection of the tumor was performed after which all patients fully recovered. There is no recurrence after 13, 11, and 5 years, respectively. CONCLUSION: CEP is a rare tumor. We diagnosed 3 paragangliomas out of a series of 105 intradural extramedullary tumors in adults (1994–2005). No recurrence was seen after total resection. In retrospect, both the intraoperative appearance and the MR image were not completely typical for schwannoma or ependymoma, but final diagnosis can only be made histologically.
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spelling pubmed-31445962011-08-02 Paraganglioma of the cauda equina region: A report of three cases Ardon, Hilko Plets, Christiaan Sciot, Raf Calenbergh, Frank Van Surg Neurol Int Case Report BACKGROUND: Cauda equina paragangliomas (CEP) are rare tumors. Low back pain and sciatica are the main presenting symptoms. Magnetic resonance imaging (MRI) is the study of choice and treatment consists of total excision when feasible. Definitive diagnosis can only be made after immunohistochemical investigation. CEP is classified as grade I WHO and after total removal the prognosis is excellent. Nonetheless, after subtotal removal, tumor recurrence can occur. CASE DESCRIPTION: We present 3 cases of CEP, preoperatively diagnosed as an intradural mass on MRI and suspected to be ependymoma. All 3 patients presented with low back pain and variable sciatic pain. Total resection of the tumor was performed after which all patients fully recovered. There is no recurrence after 13, 11, and 5 years, respectively. CONCLUSION: CEP is a rare tumor. We diagnosed 3 paragangliomas out of a series of 105 intradural extramedullary tumors in adults (1994–2005). No recurrence was seen after total resection. In retrospect, both the intraoperative appearance and the MR image were not completely typical for schwannoma or ependymoma, but final diagnosis can only be made histologically. Medknow Publications Pvt Ltd 2011-07-18 /pmc/articles/PMC3144596/ /pubmed/21811702 http://dx.doi.org/10.4103/2152-7806.82989 Text en Copyright: © 2011 Ardon H. http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Case Report
Ardon, Hilko
Plets, Christiaan
Sciot, Raf
Calenbergh, Frank Van
Paraganglioma of the cauda equina region: A report of three cases
title Paraganglioma of the cauda equina region: A report of three cases
title_full Paraganglioma of the cauda equina region: A report of three cases
title_fullStr Paraganglioma of the cauda equina region: A report of three cases
title_full_unstemmed Paraganglioma of the cauda equina region: A report of three cases
title_short Paraganglioma of the cauda equina region: A report of three cases
title_sort paraganglioma of the cauda equina region: a report of three cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144596/
https://www.ncbi.nlm.nih.gov/pubmed/21811702
http://dx.doi.org/10.4103/2152-7806.82989
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