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Inflammation and diabetic retinal microvascular complications
Diabetic retinopathy (DR) is one of the most common complications of diabetes and is a leading cause of blindness in people of the working age in Western countries. A major pathology of DR is microvascular complications such as non-perfused vessels, microaneurysms, dot/blot hemorrhages, cotton-wool...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications Pvt Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144626/ https://www.ncbi.nlm.nih.gov/pubmed/21814413 http://dx.doi.org/10.4103/0975-3583.83035 |
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author | Zhang, Wenbo Liu, Hua Al-Shabrawey, Mohamed Caldwell, Robert W. Caldwell, Ruth B. |
author_facet | Zhang, Wenbo Liu, Hua Al-Shabrawey, Mohamed Caldwell, Robert W. Caldwell, Ruth B. |
author_sort | Zhang, Wenbo |
collection | PubMed |
description | Diabetic retinopathy (DR) is one of the most common complications of diabetes and is a leading cause of blindness in people of the working age in Western countries. A major pathology of DR is microvascular complications such as non-perfused vessels, microaneurysms, dot/blot hemorrhages, cotton-wool spots, venous beading, vascular loops, vascular leakage and neovascularization. Multiple mechanisms are involved in these alternations. This review will focus on the role of inflammation in diabetic retinal microvascular complications and discuss the potential therapies by targeting inflammation. |
format | Online Article Text |
id | pubmed-3144626 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Medknow Publications Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-31446262011-08-03 Inflammation and diabetic retinal microvascular complications Zhang, Wenbo Liu, Hua Al-Shabrawey, Mohamed Caldwell, Robert W. Caldwell, Ruth B. J Cardiovasc Dis Res Invited Review Diabetic retinopathy (DR) is one of the most common complications of diabetes and is a leading cause of blindness in people of the working age in Western countries. A major pathology of DR is microvascular complications such as non-perfused vessels, microaneurysms, dot/blot hemorrhages, cotton-wool spots, venous beading, vascular loops, vascular leakage and neovascularization. Multiple mechanisms are involved in these alternations. This review will focus on the role of inflammation in diabetic retinal microvascular complications and discuss the potential therapies by targeting inflammation. Medknow Publications Pvt Ltd 2011 /pmc/articles/PMC3144626/ /pubmed/21814413 http://dx.doi.org/10.4103/0975-3583.83035 Text en © Journal of Cardiovascular Disease Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Invited Review Zhang, Wenbo Liu, Hua Al-Shabrawey, Mohamed Caldwell, Robert W. Caldwell, Ruth B. Inflammation and diabetic retinal microvascular complications |
title | Inflammation and diabetic retinal microvascular complications |
title_full | Inflammation and diabetic retinal microvascular complications |
title_fullStr | Inflammation and diabetic retinal microvascular complications |
title_full_unstemmed | Inflammation and diabetic retinal microvascular complications |
title_short | Inflammation and diabetic retinal microvascular complications |
title_sort | inflammation and diabetic retinal microvascular complications |
topic | Invited Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144626/ https://www.ncbi.nlm.nih.gov/pubmed/21814413 http://dx.doi.org/10.4103/0975-3583.83035 |
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