Cargando…
Nonsegmental Vitiligo and Autoimmune Mechanism
Nonsegmental vitiligo is a depigmented skin disorder showing acquired, progressive, and depigmented lesions of the skin, mucosa, and hair. It is believed to be caused mainly by the autoimmune loss of melanocytes from the involved areas. It is frequently associated with other autoimmune diseases, par...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144695/ https://www.ncbi.nlm.nih.gov/pubmed/21804820 http://dx.doi.org/10.1155/2011/518090 |
_version_ | 1782209028876664832 |
---|---|
author | Oiso, Naoki Suzuki, Tamio Fukai, Kazuyoshi Katayama, Ichiro Kawada, Akira |
author_facet | Oiso, Naoki Suzuki, Tamio Fukai, Kazuyoshi Katayama, Ichiro Kawada, Akira |
author_sort | Oiso, Naoki |
collection | PubMed |
description | Nonsegmental vitiligo is a depigmented skin disorder showing acquired, progressive, and depigmented lesions of the skin, mucosa, and hair. It is believed to be caused mainly by the autoimmune loss of melanocytes from the involved areas. It is frequently associated with other autoimmune diseases, particularly autoimmune thyroid diseases including Hashimoto's thyroiditis and Graves' disease, rheumatoid arthritis, type 1 diabetes, psoriasis, pernicious anemia, systemic lupus erythematosus, Addison's disease, and alopecia areata. This indicates the presence of genetically determined susceptibility to not only vitiligo but also to other autoimmune disorders. Here, we summarize current understanding of autoimmune pathogenesis in non-segmental vitiligo. |
format | Online Article Text |
id | pubmed-3144695 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-31446952011-07-29 Nonsegmental Vitiligo and Autoimmune Mechanism Oiso, Naoki Suzuki, Tamio Fukai, Kazuyoshi Katayama, Ichiro Kawada, Akira Dermatol Res Pract Review Article Nonsegmental vitiligo is a depigmented skin disorder showing acquired, progressive, and depigmented lesions of the skin, mucosa, and hair. It is believed to be caused mainly by the autoimmune loss of melanocytes from the involved areas. It is frequently associated with other autoimmune diseases, particularly autoimmune thyroid diseases including Hashimoto's thyroiditis and Graves' disease, rheumatoid arthritis, type 1 diabetes, psoriasis, pernicious anemia, systemic lupus erythematosus, Addison's disease, and alopecia areata. This indicates the presence of genetically determined susceptibility to not only vitiligo but also to other autoimmune disorders. Here, we summarize current understanding of autoimmune pathogenesis in non-segmental vitiligo. Hindawi Publishing Corporation 2011 2011-07-26 /pmc/articles/PMC3144695/ /pubmed/21804820 http://dx.doi.org/10.1155/2011/518090 Text en Copyright © 2011 Naoki Oiso et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Oiso, Naoki Suzuki, Tamio Fukai, Kazuyoshi Katayama, Ichiro Kawada, Akira Nonsegmental Vitiligo and Autoimmune Mechanism |
title | Nonsegmental Vitiligo and Autoimmune Mechanism |
title_full | Nonsegmental Vitiligo and Autoimmune Mechanism |
title_fullStr | Nonsegmental Vitiligo and Autoimmune Mechanism |
title_full_unstemmed | Nonsegmental Vitiligo and Autoimmune Mechanism |
title_short | Nonsegmental Vitiligo and Autoimmune Mechanism |
title_sort | nonsegmental vitiligo and autoimmune mechanism |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144695/ https://www.ncbi.nlm.nih.gov/pubmed/21804820 http://dx.doi.org/10.1155/2011/518090 |
work_keys_str_mv | AT oisonaoki nonsegmentalvitiligoandautoimmunemechanism AT suzukitamio nonsegmentalvitiligoandautoimmunemechanism AT fukaikazuyoshi nonsegmentalvitiligoandautoimmunemechanism AT katayamaichiro nonsegmentalvitiligoandautoimmunemechanism AT kawadaakira nonsegmentalvitiligoandautoimmunemechanism |