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Lessons from morpholino-based screening in zebrafish

Morpholino oligonucleotides (MOs) are an effective, gene-specific antisense knockdown technology used in many model systems. Here we describe the application of MOs in zebrafish (Danio rerio) for in vivo functional characterization of gene activity. We summarize our screening experience beginning wi...

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Detalles Bibliográficos
Autores principales:	Bedell, Victoria M., Westcot, Stephanie E., Ekker, Stephen C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Special Issue Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144740/ https://www.ncbi.nlm.nih.gov/pubmed/21746693 http://dx.doi.org/10.1093/bfgp/elr021

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