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Computational Reverse-Engineering of a Spider-Venom Derived Peptide Active Against Plasmodium falciparum SUB1

BACKGROUND: Psalmopeotoxin I (PcFK1), a protein of 33 aminoacids derived from the venom of the spider Psalmopoeus Cambridgei, is able to inhibit the growth of Plasmodium falciparum malaria parasites with an IC[Image: see text] in the low micromolar range. PcFK1 was proposed to act as an ion channel...

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Detalles Bibliográficos
Autores principales:	Bastianelli, Giacomo, Bouillon, Anthony, Nguyen, Christophe, Crublet, Elodie, Pêtres, Stéphane, Gorgette, Olivier, Le-Nguyen, Dung, Barale, Jean-Christophe, Nilges, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144881/ https://www.ncbi.nlm.nih.gov/pubmed/21818266 http://dx.doi.org/10.1371/journal.pone.0021812

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