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Impaired Cognitive Function and Altered Hippocampal Synapse Morphology in Mice Lacking Lrrtm1, a Gene Associated with Schizophrenia

Recent genetic linkage analysis has shown that LRRTM1 (Leucine rich repeat transmembrane neuronal 1) is associated with schizophrenia. Here, we characterized Lrrtm1 knockout mice behaviorally and morphologically. Systematic behavioral analysis revealed reduced locomotor activity in the early dark ph...

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Detalles Bibliográficos
Autores principales:	Takashima, Noriko, Odaka, Yuri S., Sakoori, Kazuto, Akagi, Takumi, Hashikawa, Tsutomu, Morimura, Naoko, Yamada, Kazuyuki, Aruga, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144940/ https://www.ncbi.nlm.nih.gov/pubmed/21818371 http://dx.doi.org/10.1371/journal.pone.0022716

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