The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial

BACKGROUND: Lowering LDL cholesterol with statin regimens reduces the risk of myocardial infarction, ischaemic stroke, and the need for coronary revascularisation in people without kidney disease, but its effects in people with moderate-to-severe kidney disease are uncertain. The SHARP trial aimed t...

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Detalles Bibliográficos
Autores principales: Baigent, Colin, Landray, Martin J, Reith, Christina, Emberson, Jonathan, Wheeler, David C, Tomson, Charles, Wanner, Christoph, Krane, Vera, Cass, Alan, Craig, Jonathan, Neal, Bruce, Jiang, Lixin, Hooi, Lai Seong, Levin, Adeera, Agodoa, Lawrence, Gaziano, Mike, Kasiske, Bertram, Walker, Robert, Massy, Ziad A, Feldt-Rasmussen, Bo, Krairittichai, Udom, Ophascharoensuk, Vuddidhej, Fellström, Bengt, Holdaas, Hallvard, Tesar, Vladimir, Wiecek, Andrzej, Grobbee, Diederick, de Zeeuw, Dick, Grönhagen-Riska, Carola, Dasgupta, Tanaji, Lewis, David, Herrington, William, Mafham, Marion, Majoni, William, Wallendszus, Karl, Grimm, Richard, Pedersen, Terje, Tobert, Jonathan, Armitage, Jane, Baxter, Alex, Bray, Christopher, Chen, Yiping, Chen, Zhengming, Hill, Michael, Knott, Carol, Parish, Sarah, Simpson, David, Sleight, Peter, Young, Alan, Collins, Rory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lancet Publishing Group 2011
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145073/
https://www.ncbi.nlm.nih.gov/pubmed/21663949
http://dx.doi.org/10.1016/S0140-6736(11)60739-3

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