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Combined logical and data-driven models for linking signalling pathways to cellular response
BACKGROUND: Signalling pathways are the cornerstone on understanding cell function and predicting cell behavior. Recently, logical models of canonical pathways have been optimised with high-throughput phosphoproteomic data to construct cell-type specific pathways. However, less is known on how signa...
Autores principales: | Melas, Ioannis N, Mitsos, Alexander, Messinis, Dimitris E, Weiss, Thomas S, Alexopoulos, Leonidas G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145575/ https://www.ncbi.nlm.nih.gov/pubmed/21729292 http://dx.doi.org/10.1186/1752-0509-5-107 |
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