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Gene-Based Tests of Association

Genome-wide association studies (GWAS) are now used routinely to identify SNPs associated with complex human phenotypes. In several cases, multiple variants within a gene contribute independently to disease risk. Here we introduce a novel Gene-Wide Significance (GWiS) test that uses greedy Bayesian...

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Detalles Bibliográficos
Autores principales:	Huang, Hailiang, Chanda, Pritam, Alonso, Alvaro, Bader, Joel S., Arking, Dan E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145613/ https://www.ncbi.nlm.nih.gov/pubmed/21829371 http://dx.doi.org/10.1371/journal.pgen.1002177

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