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Genetic Loci Associated with Plasma Phospholipid n-3 Fatty Acids: A Meta-Analysis of Genome-Wide Association Studies from the CHARGE Consortium

Long-chain n-3 polyunsaturated fatty acids (PUFAs) can derive from diet or from α-linolenic acid (ALA) by elongation and desaturation. We investigated the association of common genetic variation with plasma phospholipid levels of the four major n-3 PUFAs by performing genome-wide association studies...

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Detalles Bibliográficos
Autores principales: Lemaitre, Rozenn N., Tanaka, Toshiko, Tang, Weihong, Manichaikul, Ani, Foy, Millennia, Kabagambe, Edmond K., Nettleton, Jennifer A., King, Irena B., Weng, Lu-Chen, Bhattacharya, Sayanti, Bandinelli, Stefania, Bis, Joshua C., Rich, Stephen S., Jacobs, David R., Cherubini, Antonio, McKnight, Barbara, Liang, Shuang, Gu, Xiangjun, Rice, Kenneth, Laurie, Cathy C., Lumley, Thomas, Browning, Brian L., Psaty, Bruce M., Chen, Yii-Der I., Friedlander, Yechiel, Djousse, Luc, Wu, Jason H. Y., Siscovick, David S., Uitterlinden, André G., Arnett, Donna K., Ferrucci, Luigi, Fornage, Myriam, Tsai, Michael Y., Mozaffarian, Dariush, Steffen, Lyn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145614/
https://www.ncbi.nlm.nih.gov/pubmed/21829377
http://dx.doi.org/10.1371/journal.pgen.1002193