Gain of DNA methylation is enhanced in the absence of CTCF at the human retinoblastoma gene promoter

BACKGROUND: Long-term gene silencing throughout cell division is generally achieved by DNA methylation and other epigenetic processes. Aberrant DNA methylation is now widely recognized to be associated with cancer and other human diseases. Here we addressed the contribution of the multifunctional nu...

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Detalles Bibliográficos
Autores principales: Dávalos-Salas, Mercedes, Furlan-Magaril, Mayra, González-Buendía, Edgar, Valdes-Quezada, Christian, Ayala-Ortega, Erandi, Recillas-Targa, Félix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145615/
https://www.ncbi.nlm.nih.gov/pubmed/21663659
http://dx.doi.org/10.1186/1471-2407-11-232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145615/
https://www.ncbi.nlm.nih.gov/pubmed/21663659
http://dx.doi.org/10.1186/1471-2407-11-232

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