Cargando…

Stress-Induced PARP Activation Mediates Recruitment of Drosophila Mi-2 to Promote Heat Shock Gene Expression

Eukaryotic cells respond to genomic and environmental stresses, such as DNA damage and heat shock (HS), with the synthesis of poly-[ADP-ribose] (PAR) at specific chromatin regions, such as DNA breaks or HS genes, by PAR polymerases (PARP). Little is known about the role of this modification during c...

Descripción completa

Detalles Bibliográficos
Autores principales: Murawska, Magdalena, Hassler, Markus, Renkawitz-Pohl, Renate, Ladurner, Andreas, Brehm, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145624/
https://www.ncbi.nlm.nih.gov/pubmed/21829383
http://dx.doi.org/10.1371/journal.pgen.1002206