A Randomized Controlled Phase Ib Trial of the Malaria Vaccine Candidate GMZ2 in African Children

BACKGROUND: GMZ2 is a fusion protein of Plasmodium falciparum merozoite surface protein 3 (MSP3) and glutamate rich protein (GLURP) that mediates an immune response against the blood stage of the parasite. Two previous phase I clinical trials, one in naïve European adults and one in malaria-exposed...

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Detalles Bibliográficos
Autores principales: Bélard, Sabine, Issifou, Saadou, Hounkpatin, Aurore B., Schaumburg, Frieder, Ngoa, Ulysse Ateba, Esen, Meral, Fendel, Rolf, de Salazar, Pablo Martinez, Mürbeth, Raymund E., Milligan, Paul, Imbault, Nathalie, Imoukhuede, Egeruan Babatunde, Theisen, Michael, Jepsen, Søren, Noor, Ramadhani A., Okech, Brenda, Kremsner, Peter G., Mordmüller, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145647/
https://www.ncbi.nlm.nih.gov/pubmed/21829466
http://dx.doi.org/10.1371/journal.pone.0022525

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