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Biologic Phenotyping of the Human Small Airway Epithelial Response to Cigarette Smoking
BACKGROUND: The first changes associated with smoking are in the small airway epithelium (SAE). Given that smoking alters SAE gene expression, but only a fraction of smokers develop chronic obstructive pulmonary disease (COPD), we hypothesized that assessment of SAE genome-wide gene expression would...
Autores principales: | Tilley, Ann E., O'Connor, Timothy P., Hackett, Neil R., Strulovici-Barel, Yael, Salit, Jacqueline, Amoroso, Nancy, Zhou, Xi Kathy, Raman, Tina, Omberg, Larsson, Clark, Andrew, Mezey, Jason, Crystal, Ronald G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145669/ https://www.ncbi.nlm.nih.gov/pubmed/21829517 http://dx.doi.org/10.1371/journal.pone.0022798 |
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