Cardiomyocyte Specific Ablation of p53 Is Not Sufficient to Block Doxorubicin Induced Cardiac Fibrosis and Associated Cytoskeletal Changes

Doxorubicin (Dox) is an anthracycline used to effectively treat several forms of cancer. Unfortunately, the use of Dox is limited due to its association with cardiovascular complications which are manifested as acute and chronic cardiotoxicity. The pathophysiological mechanism of Dox induced cardiot...

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Detalles Bibliográficos
Autores principales: Feridooni, Tiam, Hotchkiss, Adam, Remley-Carr, Sarah, Saga, Yumiko, Pasumarthi, Kishore B. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145765/
https://www.ncbi.nlm.nih.gov/pubmed/21829519
http://dx.doi.org/10.1371/journal.pone.0022801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145765/
https://www.ncbi.nlm.nih.gov/pubmed/21829519
http://dx.doi.org/10.1371/journal.pone.0022801

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