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Subcellular Antigen Location Influences T-Cell Activation during Acute Infection with Toxoplasma gondii
Effective control of the intracellular protozoan parasite Toxoplasma gondii depends on the activation of antigen-specific CD8(+) T-cells that manage acute disease and prevent recrudescence during chronic infection. T-cell activation in turn, requires presentation of parasite antigens by MHC-I molecu...
Autores principales: | Gregg, Beth, Dzierszinski, Florence, Tait, Elia, Jordan, Kimberly A., Hunter, Christopher A., Roos, David S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145783/ https://www.ncbi.nlm.nih.gov/pubmed/21829561 http://dx.doi.org/10.1371/journal.pone.0022936 |
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