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Relative Solvent Accessible Surface Area Predicts Protein Conformational Changes upon Binding
Protein interactions are often accompanied by significant changes in conformation. We have analyzed the relationships between protein structures and the conformational changes they undergo upon binding. Based upon this, we introduce a simple measure, the relative solvent accessible surface area, whi...
Autores principales: | Marsh, Joseph A., Teichmann, Sarah A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145976/ https://www.ncbi.nlm.nih.gov/pubmed/21645856 http://dx.doi.org/10.1016/j.str.2011.03.010 |
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