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Fat cells reactivate quiescent neuroblasts via TOR and glial Insulin relays in Drosophila

Many stem, progenitor and cancer cells undergo periods of mitotic quiescence from which they can be reactivated(1-5). The signals triggering entry into and exit from this reversible dormant state are not well understood. In the developing Drosophila central nervous system (CNS), multipotent self-ren...

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Detalles Bibliográficos
Autores principales: Sousa-Nunes, Rita, Yee, Lih Ling, Gould, Alex P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146047/
https://www.ncbi.nlm.nih.gov/pubmed/21346761
http://dx.doi.org/10.1038/nature09867