Cargando…

Drug utilization pattern of antibacterials used in ear, nose and throat outpatient and inpatient departments of a university hospital at New Delhi, India

OBJECTIVE: We explored the antibacterial prescribing patterns of physicians in ear, nose and throat (ENT) outpatient and inpatient departments (OPD, IPD) of a University Hospital, New Delhi, India. MATERIALS AND METHODS: A prospective study was conducted, with a sample size of 276 patients, who visi...

Descripción completa

Detalles Bibliográficos
Autores principales: Ain, M. R., Shahzad, N., Aqil, M., Alam, M. S., Khanam, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications Pvt Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146095/
https://www.ncbi.nlm.nih.gov/pubmed/21814423
http://dx.doi.org/10.4103/0975-7406.62695
_version_ 1782209161658892288
author Ain, M. R.
Shahzad, N.
Aqil, M.
Alam, M. S.
Khanam, R.
author_facet Ain, M. R.
Shahzad, N.
Aqil, M.
Alam, M. S.
Khanam, R.
author_sort Ain, M. R.
collection PubMed
description OBJECTIVE: We explored the antibacterial prescribing patterns of physicians in ear, nose and throat (ENT) outpatient and inpatient departments (OPD, IPD) of a University Hospital, New Delhi, India. MATERIALS AND METHODS: A prospective study was conducted, with a sample size of 276 patients, who visited the ENT OPD and IPD over a period of 4 months. RESULTS: It was found that 62.68% were males, 26% patients were in the age group 26-35 years, followed by 22.8% belonging to the age group 26–35 years. Maximum number of patients were diagnosed with ear (37.3%) and throat (36.2%) infections. The most frequently prescribed antibacterials were β-lactams (45.52%) followed by quinolones (26.31%). The most commonly used agent in penicillins was amoxicillin and clavulanic acid (21.74%), in cepahalosporins was cefpodoxime proxetil (5.49%) and in quinolones was gemifloxacin (14.41%). Further, 66.67% of the patients received single antibacterial drug and the average number of antibacterial agents prescribed per patient per course was found to be 1.58. It was also observed that 70.71% of the antibacterials were prescribed by oral route. The most concomitant conditions were found to be diabetes (10.5%), hypertension (6.16%) and coronary heart disease (5.07%). All the drugs were prescribed by their brand names and 48.91% patients showed good adherence with the prescribed therapy. CONCLUSIONS: The present work is the maiden drug utilization study conducted in ENT department at our university hospital. It highlighted some rational prescription patterns including less utilization of antibiotics in ENT infections, good adherence by patients and prescription by brand names. The data presented here will be useful in future, long-term and more extensive drug utilization studies in the hospital and in promotion of rational prescribing and drug use in hospitals.
format Online
Article
Text
id pubmed-3146095
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher Medknow Publications Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-31460952011-08-03 Drug utilization pattern of antibacterials used in ear, nose and throat outpatient and inpatient departments of a university hospital at New Delhi, India Ain, M. R. Shahzad, N. Aqil, M. Alam, M. S. Khanam, R. J Pharm Bioallied Sci Original Article OBJECTIVE: We explored the antibacterial prescribing patterns of physicians in ear, nose and throat (ENT) outpatient and inpatient departments (OPD, IPD) of a University Hospital, New Delhi, India. MATERIALS AND METHODS: A prospective study was conducted, with a sample size of 276 patients, who visited the ENT OPD and IPD over a period of 4 months. RESULTS: It was found that 62.68% were males, 26% patients were in the age group 26-35 years, followed by 22.8% belonging to the age group 26–35 years. Maximum number of patients were diagnosed with ear (37.3%) and throat (36.2%) infections. The most frequently prescribed antibacterials were β-lactams (45.52%) followed by quinolones (26.31%). The most commonly used agent in penicillins was amoxicillin and clavulanic acid (21.74%), in cepahalosporins was cefpodoxime proxetil (5.49%) and in quinolones was gemifloxacin (14.41%). Further, 66.67% of the patients received single antibacterial drug and the average number of antibacterial agents prescribed per patient per course was found to be 1.58. It was also observed that 70.71% of the antibacterials were prescribed by oral route. The most concomitant conditions were found to be diabetes (10.5%), hypertension (6.16%) and coronary heart disease (5.07%). All the drugs were prescribed by their brand names and 48.91% patients showed good adherence with the prescribed therapy. CONCLUSIONS: The present work is the maiden drug utilization study conducted in ENT department at our university hospital. It highlighted some rational prescription patterns including less utilization of antibiotics in ENT infections, good adherence by patients and prescription by brand names. The data presented here will be useful in future, long-term and more extensive drug utilization studies in the hospital and in promotion of rational prescribing and drug use in hospitals. Medknow Publications Pvt Ltd 2010 /pmc/articles/PMC3146095/ /pubmed/21814423 http://dx.doi.org/10.4103/0975-7406.62695 Text en Copyright: © Journal of Pharmacy and Bioallied Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Ain, M. R.
Shahzad, N.
Aqil, M.
Alam, M. S.
Khanam, R.
Drug utilization pattern of antibacterials used in ear, nose and throat outpatient and inpatient departments of a university hospital at New Delhi, India
title Drug utilization pattern of antibacterials used in ear, nose and throat outpatient and inpatient departments of a university hospital at New Delhi, India
title_full Drug utilization pattern of antibacterials used in ear, nose and throat outpatient and inpatient departments of a university hospital at New Delhi, India
title_fullStr Drug utilization pattern of antibacterials used in ear, nose and throat outpatient and inpatient departments of a university hospital at New Delhi, India
title_full_unstemmed Drug utilization pattern of antibacterials used in ear, nose and throat outpatient and inpatient departments of a university hospital at New Delhi, India
title_short Drug utilization pattern of antibacterials used in ear, nose and throat outpatient and inpatient departments of a university hospital at New Delhi, India
title_sort drug utilization pattern of antibacterials used in ear, nose and throat outpatient and inpatient departments of a university hospital at new delhi, india
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146095/
https://www.ncbi.nlm.nih.gov/pubmed/21814423
http://dx.doi.org/10.4103/0975-7406.62695
work_keys_str_mv AT ainmr drugutilizationpatternofantibacterialsusedinearnoseandthroatoutpatientandinpatientdepartmentsofauniversityhospitalatnewdelhiindia
AT shahzadn drugutilizationpatternofantibacterialsusedinearnoseandthroatoutpatientandinpatientdepartmentsofauniversityhospitalatnewdelhiindia
AT aqilm drugutilizationpatternofantibacterialsusedinearnoseandthroatoutpatientandinpatientdepartmentsofauniversityhospitalatnewdelhiindia
AT alamms drugutilizationpatternofantibacterialsusedinearnoseandthroatoutpatientandinpatientdepartmentsofauniversityhospitalatnewdelhiindia
AT khanamr drugutilizationpatternofantibacterialsusedinearnoseandthroatoutpatientandinpatientdepartmentsofauniversityhospitalatnewdelhiindia