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Blunting type 1 insulin-like growth factor receptor expression exacerbates neuronal apoptosis following hypoxic/ischemic injury
BACKGROUND: Abundant experimental data have implicated an important role for insulin-like growth factor (IGF) in protecting neuronal cells from injury, including hypoxia/ischemia (H/I) injury, a major cause of neuron death. While the specific interaction of IGFs with neuronal or glial type 1 IGF rec...
Autores principales: | Liu, Wen, D'Ercole, Joseph A, Ye, Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146424/ https://www.ncbi.nlm.nih.gov/pubmed/21718528 http://dx.doi.org/10.1186/1471-2202-12-64 |
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