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A note on the use of the generalized odds ratio in meta-analysis of association studies involving bi- and tri-allelic polymorphisms

BACKGROUND: The generalized odds ratio (GOR) was recently suggested as a genetic model-free measure for association studies. However, its properties were not extensively investigated. We used Monte Carlo simulations to investigate type-I error rates, power and bias in both effect size and between-st...

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Detalles Bibliográficos
Autores principales: Pereira, Tiago V, Mingroni-Netto, Regina C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146434/
https://www.ncbi.nlm.nih.gov/pubmed/21645382
http://dx.doi.org/10.1186/1756-0500-4-172