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A note on the use of the generalized odds ratio in meta-analysis of association studies involving bi- and tri-allelic polymorphisms
BACKGROUND: The generalized odds ratio (GOR) was recently suggested as a genetic model-free measure for association studies. However, its properties were not extensively investigated. We used Monte Carlo simulations to investigate type-I error rates, power and bias in both effect size and between-st...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146434/ https://www.ncbi.nlm.nih.gov/pubmed/21645382 http://dx.doi.org/10.1186/1756-0500-4-172 |