Secreted Human Amyloid Precursor Protein Binds Semaphorin 3a and Prevents Semaphorin-Induced Growth Cone Collapse

The amyloid precursor protein (APP) is well known for giving rise to the amyloid-β peptide and for its role in Alzheimer's disease. Much less is known, however, on the physiological roles of APP in the development and plasticity of the central nervous system. We have used phage display of a pep...

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Detalles Bibliográficos
Autores principales: Magdesian, Margaret H., Gralle, Matthias, Guerreiro, Luiz H., Beltrão, Paulo José I., Carvalho, Milena M. V. F., Santos, Luís Eduardo da S., de Mello, Fernando G., Reis, Ricardo A. M., Ferreira, Sérgio T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146505/
https://www.ncbi.nlm.nih.gov/pubmed/21829538
http://dx.doi.org/10.1371/journal.pone.0022857

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