Targeting the NG2/CSPG4 Proteoglycan Retards Tumour Growth and Angiogenesis in Preclinical Models of GBM and Melanoma

Aberrant expression of the progenitor marker Neuron-glia 2 (NG2/CSPG4) or melanoma proteoglycan on cancer cells and angiogenic vasculature is associated with an aggressive disease course in several malignancies including glioblastoma multiforme (GBM) and melanoma. Thus, we investigated the mechanism...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Jian, Svendsen, Agnete, Kmiecik, Justyna, Immervoll, Heike, Skaftnesmo, Kai Ove, Planagumà, Jesús, Reed, Rolf Kåre, Bjerkvig, Rolf, Miletic, Hrvoje, Enger, Per Øyvind, Rygh, Cecilie Brekke, Chekenya, Martha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146530/
https://www.ncbi.nlm.nih.gov/pubmed/21829586
http://dx.doi.org/10.1371/journal.pone.0023062

Ejemplares similares

Ejemplares similares