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Multiple suppression pathways of canonical Wnt signalling control thymic epithelial senescence

Members of the Wnt family of secreted glyco-lipo-proteins affect intrathymic T-cell development and are abundantly secreted by thymic epithelial cells (TECs) that create the specific microenvironment for thymocytes to develop into mature T-cells. During ageing, Wnt expression declines allowing adipo...

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Detalles Bibliográficos
Autores principales: Varecza, Zoltan, Kvell, Krisztian, Talabér, Gergely, Miskei, Gyorgy, Csongei, Veronika, Bartis, Domokos, Anderson, Graham, Jenkinson, Eric J., Pongracz, Judit E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ireland 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146701/
https://www.ncbi.nlm.nih.gov/pubmed/21549744
http://dx.doi.org/10.1016/j.mad.2011.04.007