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A methodology for utilization of predictive genomic signatures in FFPE samples

BACKGROUND: Gene expression signatures developed to measure the activity of oncogenic signaling pathways have been used to dissect the heterogeneity of tumor samples and to predict sensitivity to various cancer drugs that target components of the relevant pathways, thus potentially identifying thera...

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Detalles Bibliográficos
Autores principales: Freedman, Jennifer A, Augustine, Christina K, Selim, Angelica M, Holshausen, Kirsten C, Wei, Zhengzheng, Tsamis, Katherine A, Hsu, David S, Dressman, Holly K, Barry, William T, Tyler, Douglas S, Nevins, Joseph R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146808/
https://www.ncbi.nlm.nih.gov/pubmed/21745407
http://dx.doi.org/10.1186/1755-8794-4-58