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A methodology for utilization of predictive genomic signatures in FFPE samples
BACKGROUND: Gene expression signatures developed to measure the activity of oncogenic signaling pathways have been used to dissect the heterogeneity of tumor samples and to predict sensitivity to various cancer drugs that target components of the relevant pathways, thus potentially identifying thera...
Autores principales: | Freedman, Jennifer A, Augustine, Christina K, Selim, Angelica M, Holshausen, Kirsten C, Wei, Zhengzheng, Tsamis, Katherine A, Hsu, David S, Dressman, Holly K, Barry, William T, Tyler, Douglas S, Nevins, Joseph R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146808/ https://www.ncbi.nlm.nih.gov/pubmed/21745407 http://dx.doi.org/10.1186/1755-8794-4-58 |
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