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Peptide binding prediction for the human class II MHC allele HLA-DP2: a molecular docking approach

BACKGROUND: MHC class II proteins bind oligopeptide fragments derived from proteolysis of pathogen antigens, presenting them at the cell surface for recognition by CD4+ T cells. Human MHC class II alleles are grouped into three loci: HLA-DP, HLA-DQ and HLA-DR. In contrast to HLA-DR and HLA-DQ, HLA-D...

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Detalles Bibliográficos
Autores principales: Patronov, Atanas, Dimitrov, Ivan, Flower, Darren R, Doytchinova, Irini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146810/
https://www.ncbi.nlm.nih.gov/pubmed/21752305
http://dx.doi.org/10.1186/1472-6807-11-32