The crystal structure of alanine racemase from Streptococcus pneumoniae, a target for structure-based drug design

BACKGROUND: Streptococcus pneumoniae is a globally important pathogen. The Gram-positive diplococcus is a leading cause of pneumonia, otitis media, bacteremia, and meningitis, and antibiotic resistant strains have become increasingly common over recent years. Alanine racemase is a ubiquitous enzyme...

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Detalles Bibliográficos
Autores principales: Im, Hookang, Sharpe, Miriam L, Strych, Ulrich, Davlieva, Milya, Krause, Kurt L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146814/
https://www.ncbi.nlm.nih.gov/pubmed/21612658
http://dx.doi.org/10.1186/1471-2180-11-116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146814/
https://www.ncbi.nlm.nih.gov/pubmed/21612658
http://dx.doi.org/10.1186/1471-2180-11-116

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