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Multiplex Zymography Captures Stage-specific Activity Profiles of Cathepsins K, L, and S in Human Breast, Lung, and Cervical Cancer

BACKGROUND: Cathepsins K, L, and S are cysteine proteases upregulated in cancer and proteolyze extracellular matrix to facilitate metastasis, but difficulty distinguishing specific cathepsin activity in complex tissue extracts confounds scientific studies and employing them for use in clinical diagn...

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Detalles Bibliográficos
Autores principales:	Chen, Binbin, Platt, Manu O
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146840/ https://www.ncbi.nlm.nih.gov/pubmed/21756348 http://dx.doi.org/10.1186/1479-5876-9-109

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