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Granulocyte colony stimulating factor attenuates inflammation in a mouse model of amyotrophic lateral sclerosis
BACKGROUND: Granulocyte colony stimulating factor (GCSF) is protective in animal models of various neurodegenerative diseases. We investigated whether pegfilgrastim, GCSF with sustained action, is protective in a mouse model of amyotrophic lateral sclerosis (ALS). ALS is a fatal neurodegenerative di...
Autores principales: | Pollari, Eveliina, Savchenko, Ekaterina, Jaronen, Merja, Kanninen, Katja, Malm, Tarja, Wojciechowski, Sara, Ahtoniemi, Toni, Goldsteins, Gundars, Giniatullina, Raisa, Giniatullin, Rashid, Koistinaho, Jari, Magga, Johanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146845/ https://www.ncbi.nlm.nih.gov/pubmed/21711557 http://dx.doi.org/10.1186/1742-2094-8-74 |
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