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Exploring the selective constraint on the sizes of insertions and deletions in 5' untranslated regions in mammals
BACKGROUND: Small insertions and deletions ("indels" with size ≦ 100 bp) whose lengths are not multiples of three (non-3n) are strongly constrained and depleted in protein-coding sequences. Such a constraint has never been reported in noncoding genomic regions. In 5'untranslated regio...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146882/ https://www.ncbi.nlm.nih.gov/pubmed/21726469 http://dx.doi.org/10.1186/1471-2148-11-192 |