Plasmodium falciparum isolates from southern Ghana exhibit polymorphisms in the SERCA-type PfATPase6 though sensitive to artesunate in vitro

BACKGROUND: In 2005, Ghana replaced chloroquine with artemisinin-based combination therapy as the first-line treatment for uncomplicated malaria. The aim of this work was to determine for the first time, polymorphisms in the putative pfATPase6 and pftctp, pfmdr1, pfcrt genes in Ghanaian isolates, pa...

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Detalles Bibliográficos
Autores principales: Kwansa-Bentum, Bethel, Ayi, Irene, Suzuki, Takashi, Otchere, Joseph, Kumagai, Takashi, Anyan, William K, Osei, Joseph HN, Asahi, Hiroko, Ofori, Michael F, Akao, Nobuaki, Wilson, Michael D, Boakye, Daniel A, Ohta, Nobuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146903/
https://www.ncbi.nlm.nih.gov/pubmed/21745377
http://dx.doi.org/10.1186/1475-2875-10-187

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