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Sustained platelet-sparing effect of weekly low dose paclitaxel allows effective, tolerable delivery of extended dose dense weekly carboplatin in platinum resistant/refractory epithelial ovarian cancer

BACKGROUND: Platinum agents have shown demonstrable activity in the treatment of patients with platinum resistant, recurrent ovarian cancer when delivered in a "dose-dense" fashion. However, the development of thrombocytopenia limits the weekly administration of carboplatin to no greater t...

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Detalles Bibliográficos
Autores principales: Sharma, Rohini, Graham, Janet, Blagden, Sarah, Gabra, Hani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146942/
https://www.ncbi.nlm.nih.gov/pubmed/21745358
http://dx.doi.org/10.1186/1471-2407-11-289