Cargando…
IL-6 promotes acute and chronic inflammatory disease in the absence of SOCS3
The lack of expression of the Suppressor of Cytokine Signalling-3 (SOCS3) or inactivation of the negative regulatory capacity of SOCS3 has been well documented in rheumatoid arthritis, viral hepatitis and cancer. The specific qualitative and quantitative consequences of SOCS3-deficiency on IL-6-medi...
Autores principales: | Croker, Ben A, Kiu, Hiu, Pellegrini, Marc, Toe, Jesse, Preston, Simon, Metcalf, Donald, O’Donnell, Joanne A, Cengia, Louise H, McArthur, Kate, Nicola, Nicos A, Alexander, Warren S, Roberts, Andrew W |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146962/ https://www.ncbi.nlm.nih.gov/pubmed/21519345 http://dx.doi.org/10.1038/icb.2011.29 |
Ejemplares similares
-
Rapid Inflammation in Mice Lacking Both SOCS1 and SOCS3 in Hematopoietic Cells
por: Ushiki, Takashi, et al.
Publicado: (2016) -
Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β
por: Kim, Man Lyang, et al.
Publicado: (2015) -
SOCS3: An essential physiological inhibitor of signaling by interleukin-6 and G-CSF family cytokines
por: White, Christine A, et al.
Publicado: (2013) -
Defining a therapeutic window for kinase inhibitors in leukemia to avoid neutropenia
por: McArthur, Kate, et al.
Publicado: (2017) -
Increased linear bone growth by GH in the absence of SOCS2 is independent of IGF‐1
por: Dobie, Ross, et al.
Publicado: (2015)