Genetically Modified Lactococcus lactis for Delivery of Human Interleukin-10 to Dendritic Cells

Interleukin-10 (IL-10) plays an indispensable role in mucosal tolerance by programming dendritic cells (DCs) to induce suppressor Th-cells. We have tested the modulating effect of L. lactis secreting human IL-10 (L.  lactis (IL-10)) on DC function in vitro. Monocyte-derived DC incubated with L.  lac...

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Detalles Bibliográficos
Autores principales: Huibregtse, Inge L., Zaat, Sebatian A., Kapsenberg, Martien L., Sartori da Silva, Maria A., Peppelenbosch, Maikel P., van Deventer, Sander J. H., Braat, Henri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146989/
https://www.ncbi.nlm.nih.gov/pubmed/21811497
http://dx.doi.org/10.1155/2012/639291

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