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Prognosis of Thyroid Cancer Related to Pregnancy: A Systematic Review

Differentiated thyroid cancer (DTC) is the second most common cancer in pregnancy. Its management is a challenge for both doctors and patients, and the best timing for surgery is unclear. A systematic review evaluating the prognosis of DTC in pregnant patients was conducted. After reviewing 401 uniq...

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Autores principales: Alves, Gustavo Vasconcelos, Santin, Ana Paula, Furlanetto, Tania Weber
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146994/
https://www.ncbi.nlm.nih.gov/pubmed/21811666
http://dx.doi.org/10.4061/2011/691719
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author Alves, Gustavo Vasconcelos
Santin, Ana Paula
Furlanetto, Tania Weber
author_facet Alves, Gustavo Vasconcelos
Santin, Ana Paula
Furlanetto, Tania Weber
author_sort Alves, Gustavo Vasconcelos
collection PubMed
description Differentiated thyroid cancer (DTC) is the second most common cancer in pregnancy. Its management is a challenge for both doctors and patients, and the best timing for surgery is unclear. A systematic review evaluating the prognosis of DTC in pregnant patients was conducted. After reviewing 401 unique citations and 54 full texts, 4 studies that compared the prognosis of patients with DTC related to pregnancy (DTC diagnosed during pregnancy or within 12 months after childbirth) or not were included. In two studies the primary outcome was overall survival, in one study the primary outcomes were recurrent disease and death related to thyroid cancer, and in one study the primary outcome was recurrent or persistent disease. In the first two studies, there was no difference in overall survival in patients with pregnancy-related DTC, when compared with matched controls; in one study, there was no difference in death caused by DTC nor recurrence in DTC related to pregnancy. Nevertheless, in a recent retrospective study, a higher rate of recurrent or persistent DTC was observed in patients with DTC related to pregnancy. There are not many studies on which to base treatment decisions in pregnant patients with DTC.
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spelling pubmed-31469942011-08-02 Prognosis of Thyroid Cancer Related to Pregnancy: A Systematic Review Alves, Gustavo Vasconcelos Santin, Ana Paula Furlanetto, Tania Weber J Thyroid Res Review Article Differentiated thyroid cancer (DTC) is the second most common cancer in pregnancy. Its management is a challenge for both doctors and patients, and the best timing for surgery is unclear. A systematic review evaluating the prognosis of DTC in pregnant patients was conducted. After reviewing 401 unique citations and 54 full texts, 4 studies that compared the prognosis of patients with DTC related to pregnancy (DTC diagnosed during pregnancy or within 12 months after childbirth) or not were included. In two studies the primary outcome was overall survival, in one study the primary outcomes were recurrent disease and death related to thyroid cancer, and in one study the primary outcome was recurrent or persistent disease. In the first two studies, there was no difference in overall survival in patients with pregnancy-related DTC, when compared with matched controls; in one study, there was no difference in death caused by DTC nor recurrence in DTC related to pregnancy. Nevertheless, in a recent retrospective study, a higher rate of recurrent or persistent DTC was observed in patients with DTC related to pregnancy. There are not many studies on which to base treatment decisions in pregnant patients with DTC. SAGE-Hindawi Access to Research 2011-07-27 /pmc/articles/PMC3146994/ /pubmed/21811666 http://dx.doi.org/10.4061/2011/691719 Text en Copyright © 2011 Gustavo Vasconcelos Alves et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Alves, Gustavo Vasconcelos
Santin, Ana Paula
Furlanetto, Tania Weber
Prognosis of Thyroid Cancer Related to Pregnancy: A Systematic Review
title Prognosis of Thyroid Cancer Related to Pregnancy: A Systematic Review
title_full Prognosis of Thyroid Cancer Related to Pregnancy: A Systematic Review
title_fullStr Prognosis of Thyroid Cancer Related to Pregnancy: A Systematic Review
title_full_unstemmed Prognosis of Thyroid Cancer Related to Pregnancy: A Systematic Review
title_short Prognosis of Thyroid Cancer Related to Pregnancy: A Systematic Review
title_sort prognosis of thyroid cancer related to pregnancy: a systematic review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146994/
https://www.ncbi.nlm.nih.gov/pubmed/21811666
http://dx.doi.org/10.4061/2011/691719
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