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Prognosis of Thyroid Cancer Related to Pregnancy: A Systematic Review
Differentiated thyroid cancer (DTC) is the second most common cancer in pregnancy. Its management is a challenge for both doctors and patients, and the best timing for surgery is unclear. A systematic review evaluating the prognosis of DTC in pregnant patients was conducted. After reviewing 401 uniq...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE-Hindawi Access to Research
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146994/ https://www.ncbi.nlm.nih.gov/pubmed/21811666 http://dx.doi.org/10.4061/2011/691719 |
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author | Alves, Gustavo Vasconcelos Santin, Ana Paula Furlanetto, Tania Weber |
author_facet | Alves, Gustavo Vasconcelos Santin, Ana Paula Furlanetto, Tania Weber |
author_sort | Alves, Gustavo Vasconcelos |
collection | PubMed |
description | Differentiated thyroid cancer (DTC) is the second most common cancer in pregnancy. Its management is a challenge for both doctors and patients, and the best timing for surgery is unclear. A systematic review evaluating the prognosis of DTC in pregnant patients was conducted. After reviewing 401 unique citations and 54 full texts, 4 studies that compared the prognosis of patients with DTC related to pregnancy (DTC diagnosed during pregnancy or within 12 months after childbirth) or not were included. In two studies the primary outcome was overall survival, in one study the primary outcomes were recurrent disease and death related to thyroid cancer, and in one study the primary outcome was recurrent or persistent disease. In the first two studies, there was no difference in overall survival in patients with pregnancy-related DTC, when compared with matched controls; in one study, there was no difference in death caused by DTC nor recurrence in DTC related to pregnancy. Nevertheless, in a recent retrospective study, a higher rate of recurrent or persistent DTC was observed in patients with DTC related to pregnancy. There are not many studies on which to base treatment decisions in pregnant patients with DTC. |
format | Online Article Text |
id | pubmed-3146994 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | SAGE-Hindawi Access to Research |
record_format | MEDLINE/PubMed |
spelling | pubmed-31469942011-08-02 Prognosis of Thyroid Cancer Related to Pregnancy: A Systematic Review Alves, Gustavo Vasconcelos Santin, Ana Paula Furlanetto, Tania Weber J Thyroid Res Review Article Differentiated thyroid cancer (DTC) is the second most common cancer in pregnancy. Its management is a challenge for both doctors and patients, and the best timing for surgery is unclear. A systematic review evaluating the prognosis of DTC in pregnant patients was conducted. After reviewing 401 unique citations and 54 full texts, 4 studies that compared the prognosis of patients with DTC related to pregnancy (DTC diagnosed during pregnancy or within 12 months after childbirth) or not were included. In two studies the primary outcome was overall survival, in one study the primary outcomes were recurrent disease and death related to thyroid cancer, and in one study the primary outcome was recurrent or persistent disease. In the first two studies, there was no difference in overall survival in patients with pregnancy-related DTC, when compared with matched controls; in one study, there was no difference in death caused by DTC nor recurrence in DTC related to pregnancy. Nevertheless, in a recent retrospective study, a higher rate of recurrent or persistent DTC was observed in patients with DTC related to pregnancy. There are not many studies on which to base treatment decisions in pregnant patients with DTC. SAGE-Hindawi Access to Research 2011-07-27 /pmc/articles/PMC3146994/ /pubmed/21811666 http://dx.doi.org/10.4061/2011/691719 Text en Copyright © 2011 Gustavo Vasconcelos Alves et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Alves, Gustavo Vasconcelos Santin, Ana Paula Furlanetto, Tania Weber Prognosis of Thyroid Cancer Related to Pregnancy: A Systematic Review |
title | Prognosis of Thyroid Cancer Related to Pregnancy: A Systematic Review |
title_full | Prognosis of Thyroid Cancer Related to Pregnancy: A Systematic Review |
title_fullStr | Prognosis of Thyroid Cancer Related to Pregnancy: A Systematic Review |
title_full_unstemmed | Prognosis of Thyroid Cancer Related to Pregnancy: A Systematic Review |
title_short | Prognosis of Thyroid Cancer Related to Pregnancy: A Systematic Review |
title_sort | prognosis of thyroid cancer related to pregnancy: a systematic review |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146994/ https://www.ncbi.nlm.nih.gov/pubmed/21811666 http://dx.doi.org/10.4061/2011/691719 |
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