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A simple model based on mutation and selection explains trends in codon and amino-acid usage and GC composition within and across genomes

BACKGROUND: Correlations between genome composition (in terms of GC content) and usage of particular codons and amino acids have been widely reported, but poorly explained. We show here that a simple model of processes acting at the nucleotide level explains codon usage across a large sample of spec...

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Detalles Bibliográficos
Autores principales: Knight, Robin D, Freeland, Stephen J, Landweber, Laura F
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC31479/
https://www.ncbi.nlm.nih.gov/pubmed/11305938