Circulating Strains of Human Respiratory Syncytial Virus in Central and South America

Human respiratory syncytial virus (HRSV) is a major cause of viral lower respiratory tract infections among infants and young children. HRSV strains vary genetically and antigenically and have been classified into two broad subgroups, A and B (HRSV-A and HRSV-B, respectively). To date, little is kno...

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Detalles Bibliográficos
Autores principales: Sovero, Merly, Garcia, Josefina, Kochel, Tadeusz, Laguna-Torres, V. Alberto, Gomez, Jorge, Chicaiza, Wilson, Barrantes, Melvin, Sanchez, Felix, Jimenez, Mirna, Comach, Guillermo, de Rivera, Ivette Lorenzana, Arango, Ana E., Agudo, Roberto, Halsey, Eric S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148217/
https://www.ncbi.nlm.nih.gov/pubmed/21829605
http://dx.doi.org/10.1371/journal.pone.0022111
Descripción
Sumario:Human respiratory syncytial virus (HRSV) is a major cause of viral lower respiratory tract infections among infants and young children. HRSV strains vary genetically and antigenically and have been classified into two broad subgroups, A and B (HRSV-A and HRSV-B, respectively). To date, little is known about the circulating strains of HRSV in Latin America. We have evaluated the genetic diversity of 96 HRSV strains by sequencing a variable region of the G protein gene of isolates collected from 2007 to 2009 in Central and South America. Our results show the presence of the two antigenic subgroups of HRSV during this period with the majority belonging to the genotype HRSV-A2.

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