Cargando…

Circulating Strains of Human Respiratory Syncytial Virus in Central and South America

Human respiratory syncytial virus (HRSV) is a major cause of viral lower respiratory tract infections among infants and young children. HRSV strains vary genetically and antigenically and have been classified into two broad subgroups, A and B (HRSV-A and HRSV-B, respectively). To date, little is kno...

Descripción completa

Detalles Bibliográficos
Autores principales: Sovero, Merly, Garcia, Josefina, Kochel, Tadeusz, Laguna-Torres, V. Alberto, Gomez, Jorge, Chicaiza, Wilson, Barrantes, Melvin, Sanchez, Felix, Jimenez, Mirna, Comach, Guillermo, de Rivera, Ivette Lorenzana, Arango, Ana E., Agudo, Roberto, Halsey, Eric S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148217/
https://www.ncbi.nlm.nih.gov/pubmed/21829605
http://dx.doi.org/10.1371/journal.pone.0022111
_version_ 1782209325445414912
author Sovero, Merly
Garcia, Josefina
Kochel, Tadeusz
Laguna-Torres, V. Alberto
Gomez, Jorge
Chicaiza, Wilson
Barrantes, Melvin
Sanchez, Felix
Jimenez, Mirna
Comach, Guillermo
de Rivera, Ivette Lorenzana
Arango, Ana E.
Agudo, Roberto
Halsey, Eric S.
author_facet Sovero, Merly
Garcia, Josefina
Kochel, Tadeusz
Laguna-Torres, V. Alberto
Gomez, Jorge
Chicaiza, Wilson
Barrantes, Melvin
Sanchez, Felix
Jimenez, Mirna
Comach, Guillermo
de Rivera, Ivette Lorenzana
Arango, Ana E.
Agudo, Roberto
Halsey, Eric S.
author_sort Sovero, Merly
collection PubMed
description Human respiratory syncytial virus (HRSV) is a major cause of viral lower respiratory tract infections among infants and young children. HRSV strains vary genetically and antigenically and have been classified into two broad subgroups, A and B (HRSV-A and HRSV-B, respectively). To date, little is known about the circulating strains of HRSV in Latin America. We have evaluated the genetic diversity of 96 HRSV strains by sequencing a variable region of the G protein gene of isolates collected from 2007 to 2009 in Central and South America. Our results show the presence of the two antigenic subgroups of HRSV during this period with the majority belonging to the genotype HRSV-A2.
format Online
Article
Text
id pubmed-3148217
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-31482172011-08-09 Circulating Strains of Human Respiratory Syncytial Virus in Central and South America Sovero, Merly Garcia, Josefina Kochel, Tadeusz Laguna-Torres, V. Alberto Gomez, Jorge Chicaiza, Wilson Barrantes, Melvin Sanchez, Felix Jimenez, Mirna Comach, Guillermo de Rivera, Ivette Lorenzana Arango, Ana E. Agudo, Roberto Halsey, Eric S. PLoS One Research Article Human respiratory syncytial virus (HRSV) is a major cause of viral lower respiratory tract infections among infants and young children. HRSV strains vary genetically and antigenically and have been classified into two broad subgroups, A and B (HRSV-A and HRSV-B, respectively). To date, little is known about the circulating strains of HRSV in Latin America. We have evaluated the genetic diversity of 96 HRSV strains by sequencing a variable region of the G protein gene of isolates collected from 2007 to 2009 in Central and South America. Our results show the presence of the two antigenic subgroups of HRSV during this period with the majority belonging to the genotype HRSV-A2. Public Library of Science 2011-08-01 /pmc/articles/PMC3148217/ /pubmed/21829605 http://dx.doi.org/10.1371/journal.pone.0022111 Text en This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication. https://creativecommons.org/publicdomain/zero/1.0/ This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.
spellingShingle Research Article
Sovero, Merly
Garcia, Josefina
Kochel, Tadeusz
Laguna-Torres, V. Alberto
Gomez, Jorge
Chicaiza, Wilson
Barrantes, Melvin
Sanchez, Felix
Jimenez, Mirna
Comach, Guillermo
de Rivera, Ivette Lorenzana
Arango, Ana E.
Agudo, Roberto
Halsey, Eric S.
Circulating Strains of Human Respiratory Syncytial Virus in Central and South America
title Circulating Strains of Human Respiratory Syncytial Virus in Central and South America
title_full Circulating Strains of Human Respiratory Syncytial Virus in Central and South America
title_fullStr Circulating Strains of Human Respiratory Syncytial Virus in Central and South America
title_full_unstemmed Circulating Strains of Human Respiratory Syncytial Virus in Central and South America
title_short Circulating Strains of Human Respiratory Syncytial Virus in Central and South America
title_sort circulating strains of human respiratory syncytial virus in central and south america
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148217/
https://www.ncbi.nlm.nih.gov/pubmed/21829605
http://dx.doi.org/10.1371/journal.pone.0022111
work_keys_str_mv AT soveromerly circulatingstrainsofhumanrespiratorysyncytialvirusincentralandsouthamerica
AT garciajosefina circulatingstrainsofhumanrespiratorysyncytialvirusincentralandsouthamerica
AT kocheltadeusz circulatingstrainsofhumanrespiratorysyncytialvirusincentralandsouthamerica
AT lagunatorresvalberto circulatingstrainsofhumanrespiratorysyncytialvirusincentralandsouthamerica
AT gomezjorge circulatingstrainsofhumanrespiratorysyncytialvirusincentralandsouthamerica
AT chicaizawilson circulatingstrainsofhumanrespiratorysyncytialvirusincentralandsouthamerica
AT barrantesmelvin circulatingstrainsofhumanrespiratorysyncytialvirusincentralandsouthamerica
AT sanchezfelix circulatingstrainsofhumanrespiratorysyncytialvirusincentralandsouthamerica
AT jimenezmirna circulatingstrainsofhumanrespiratorysyncytialvirusincentralandsouthamerica
AT comachguillermo circulatingstrainsofhumanrespiratorysyncytialvirusincentralandsouthamerica
AT deriveraivettelorenzana circulatingstrainsofhumanrespiratorysyncytialvirusincentralandsouthamerica
AT arangoanae circulatingstrainsofhumanrespiratorysyncytialvirusincentralandsouthamerica
AT agudoroberto circulatingstrainsofhumanrespiratorysyncytialvirusincentralandsouthamerica
AT halseyerics circulatingstrainsofhumanrespiratorysyncytialvirusincentralandsouthamerica