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Circulating Strains of Human Respiratory Syncytial Virus in Central and South America
Human respiratory syncytial virus (HRSV) is a major cause of viral lower respiratory tract infections among infants and young children. HRSV strains vary genetically and antigenically and have been classified into two broad subgroups, A and B (HRSV-A and HRSV-B, respectively). To date, little is kno...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148217/ https://www.ncbi.nlm.nih.gov/pubmed/21829605 http://dx.doi.org/10.1371/journal.pone.0022111 |
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author | Sovero, Merly Garcia, Josefina Kochel, Tadeusz Laguna-Torres, V. Alberto Gomez, Jorge Chicaiza, Wilson Barrantes, Melvin Sanchez, Felix Jimenez, Mirna Comach, Guillermo de Rivera, Ivette Lorenzana Arango, Ana E. Agudo, Roberto Halsey, Eric S. |
author_facet | Sovero, Merly Garcia, Josefina Kochel, Tadeusz Laguna-Torres, V. Alberto Gomez, Jorge Chicaiza, Wilson Barrantes, Melvin Sanchez, Felix Jimenez, Mirna Comach, Guillermo de Rivera, Ivette Lorenzana Arango, Ana E. Agudo, Roberto Halsey, Eric S. |
author_sort | Sovero, Merly |
collection | PubMed |
description | Human respiratory syncytial virus (HRSV) is a major cause of viral lower respiratory tract infections among infants and young children. HRSV strains vary genetically and antigenically and have been classified into two broad subgroups, A and B (HRSV-A and HRSV-B, respectively). To date, little is known about the circulating strains of HRSV in Latin America. We have evaluated the genetic diversity of 96 HRSV strains by sequencing a variable region of the G protein gene of isolates collected from 2007 to 2009 in Central and South America. Our results show the presence of the two antigenic subgroups of HRSV during this period with the majority belonging to the genotype HRSV-A2. |
format | Online Article Text |
id | pubmed-3148217 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-31482172011-08-09 Circulating Strains of Human Respiratory Syncytial Virus in Central and South America Sovero, Merly Garcia, Josefina Kochel, Tadeusz Laguna-Torres, V. Alberto Gomez, Jorge Chicaiza, Wilson Barrantes, Melvin Sanchez, Felix Jimenez, Mirna Comach, Guillermo de Rivera, Ivette Lorenzana Arango, Ana E. Agudo, Roberto Halsey, Eric S. PLoS One Research Article Human respiratory syncytial virus (HRSV) is a major cause of viral lower respiratory tract infections among infants and young children. HRSV strains vary genetically and antigenically and have been classified into two broad subgroups, A and B (HRSV-A and HRSV-B, respectively). To date, little is known about the circulating strains of HRSV in Latin America. We have evaluated the genetic diversity of 96 HRSV strains by sequencing a variable region of the G protein gene of isolates collected from 2007 to 2009 in Central and South America. Our results show the presence of the two antigenic subgroups of HRSV during this period with the majority belonging to the genotype HRSV-A2. Public Library of Science 2011-08-01 /pmc/articles/PMC3148217/ /pubmed/21829605 http://dx.doi.org/10.1371/journal.pone.0022111 Text en This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication. https://creativecommons.org/publicdomain/zero/1.0/ This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. |
spellingShingle | Research Article Sovero, Merly Garcia, Josefina Kochel, Tadeusz Laguna-Torres, V. Alberto Gomez, Jorge Chicaiza, Wilson Barrantes, Melvin Sanchez, Felix Jimenez, Mirna Comach, Guillermo de Rivera, Ivette Lorenzana Arango, Ana E. Agudo, Roberto Halsey, Eric S. Circulating Strains of Human Respiratory Syncytial Virus in Central and South America |
title | Circulating Strains of Human Respiratory Syncytial Virus in Central and South America |
title_full | Circulating Strains of Human Respiratory Syncytial Virus in Central and South America |
title_fullStr | Circulating Strains of Human Respiratory Syncytial Virus in Central and South America |
title_full_unstemmed | Circulating Strains of Human Respiratory Syncytial Virus in Central and South America |
title_short | Circulating Strains of Human Respiratory Syncytial Virus in Central and South America |
title_sort | circulating strains of human respiratory syncytial virus in central and south america |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148217/ https://www.ncbi.nlm.nih.gov/pubmed/21829605 http://dx.doi.org/10.1371/journal.pone.0022111 |
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