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Survivin Inhibition Is Critical for Bcl-2 Inhibitor-Induced Apoptosis in Hepatocellular Carcinoma Cells

Our study aims to study the therapeutic effects of a novel Bcl-2 inhibitor, ABT-263, on hepatocellular carcinoma (HCC) and to provide primary preclinical data for future clinical trial with ABT-263. In this study we showed that Bcl-xL and survivin were up-regulated in HCC cell lines and human liver...

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Detalles Bibliográficos
Autores principales:	Zhao, Xiangxuan, Ogunwobi, Olorunseun O., Liu, Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148218/ https://www.ncbi.nlm.nih.gov/pubmed/21829603 http://dx.doi.org/10.1371/journal.pone.0021980

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