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Paradoxical Regulation of Human FGF21 by Both Fasting and Feeding Signals: Is FGF21 a Nutritional Adaptation Factor?

Fibroblast growth factor 21 (FGF21) has recently emerged as a metabolic hormone involved in regulating glucose and lipid metabolism in mouse, but the regulatory mechanisms and actions of FGF21 in humans remain unclear. Here we have investigated the regulatory mechanisms of the human FGF21 gene at th...

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Detalles Bibliográficos
Autores principales: Uebanso, Takashi, Taketani, Yutaka, Yamamoto, Hironori, Amo, Kikuko, Ominami, Hirokazu, Arai, Hidekazu, Takei, Yuichiro, Masuda, Masashi, Tanimura, Ayako, Harada, Nagakatsu, Yamanaka-Okumura, Hisami, Takeda, Eiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148241/
https://www.ncbi.nlm.nih.gov/pubmed/21829679
http://dx.doi.org/10.1371/journal.pone.0022976