Cembranoids with 3,14-Ether Linkage and a Secocembrane with Bistetrahydrofuran from the Dongsha Atoll Soft Coral Lobophytum sp.

Four new cembranoids, lobophylins A–D (1–4), and one novel secocembrane, lobophylin E (5) were isolated from a soft coral Lobophytum sp. The structures of new metabolites were elucidated on the basis of extensive spectroscopic methods. Among these metabolites, 1–4 are rarely found cembranoids posses...

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Autores principales: Hegazy, Mohamed Elamir F., Su, Jui-Hsin, Sung, Ping-Jyun, Sheu, Jyh-Horng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148501/
https://www.ncbi.nlm.nih.gov/pubmed/21822414
http://dx.doi.org/10.3390/md9071243
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author Hegazy, Mohamed Elamir F.
Su, Jui-Hsin
Sung, Ping-Jyun
Sheu, Jyh-Horng
author_facet Hegazy, Mohamed Elamir F.
Su, Jui-Hsin
Sung, Ping-Jyun
Sheu, Jyh-Horng
author_sort Hegazy, Mohamed Elamir F.
collection PubMed
description Four new cembranoids, lobophylins A–D (1–4), and one novel secocembrane, lobophylin E (5) were isolated from a soft coral Lobophytum sp. The structures of new metabolites were elucidated on the basis of extensive spectroscopic methods. Among these metabolites, 1–4 are rarely found cembranoids possessing a tetrahydrofuran moiety with a 3,14-ether linkage. In addition, 5 is the first secocembrane possessing two tetrahydrofuran moieties with 3,14- and 4,7-ether linkages.
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spelling pubmed-31485012011-08-05 Cembranoids with 3,14-Ether Linkage and a Secocembrane with Bistetrahydrofuran from the Dongsha Atoll Soft Coral Lobophytum sp. Hegazy, Mohamed Elamir F. Su, Jui-Hsin Sung, Ping-Jyun Sheu, Jyh-Horng Mar Drugs Article Four new cembranoids, lobophylins A–D (1–4), and one novel secocembrane, lobophylin E (5) were isolated from a soft coral Lobophytum sp. The structures of new metabolites were elucidated on the basis of extensive spectroscopic methods. Among these metabolites, 1–4 are rarely found cembranoids possessing a tetrahydrofuran moiety with a 3,14-ether linkage. In addition, 5 is the first secocembrane possessing two tetrahydrofuran moieties with 3,14- and 4,7-ether linkages. Molecular Diversity Preservation International 2011-07-12 /pmc/articles/PMC3148501/ /pubmed/21822414 http://dx.doi.org/10.3390/md9071243 Text en © 2011 by the authors; licensee MDPI, Basel, Switzerland http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Hegazy, Mohamed Elamir F.
Su, Jui-Hsin
Sung, Ping-Jyun
Sheu, Jyh-Horng
Cembranoids with 3,14-Ether Linkage and a Secocembrane with Bistetrahydrofuran from the Dongsha Atoll Soft Coral Lobophytum sp.
title Cembranoids with 3,14-Ether Linkage and a Secocembrane with Bistetrahydrofuran from the Dongsha Atoll Soft Coral Lobophytum sp.
title_full Cembranoids with 3,14-Ether Linkage and a Secocembrane with Bistetrahydrofuran from the Dongsha Atoll Soft Coral Lobophytum sp.
title_fullStr Cembranoids with 3,14-Ether Linkage and a Secocembrane with Bistetrahydrofuran from the Dongsha Atoll Soft Coral Lobophytum sp.
title_full_unstemmed Cembranoids with 3,14-Ether Linkage and a Secocembrane with Bistetrahydrofuran from the Dongsha Atoll Soft Coral Lobophytum sp.
title_short Cembranoids with 3,14-Ether Linkage and a Secocembrane with Bistetrahydrofuran from the Dongsha Atoll Soft Coral Lobophytum sp.
title_sort cembranoids with 3,14-ether linkage and a secocembrane with bistetrahydrofuran from the dongsha atoll soft coral lobophytum sp.
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148501/
https://www.ncbi.nlm.nih.gov/pubmed/21822414
http://dx.doi.org/10.3390/md9071243
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