Cargando…

Overexpression of MMP-9 and HIF-1α in Breast Cancer Cells under Hypoxic Conditions

PURPOSE: Hypoxia, which is a loss of oxygen in tissues, is a common condition in solid tumors due to the tumor outgrowing existing vasculature. Under hypoxic conditions, hypoxia-inducible factor (HIF)-1α rapidly accumulates and transactivates hundreds of genes, such as matrix metalloproteinases (MMP...

Descripción completa

Detalles Bibliográficos
Autores principales:	Choi, Jae Young, Jang, Yeon Soo, Min, Sun Young, Song, Jeong Yoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Breast Cancer Society 2011
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148536/ https://www.ncbi.nlm.nih.gov/pubmed/21847402 http://dx.doi.org/10.4048/jbc.2011.14.2.88

Ejemplares similares

Thrombotic Alterations under Perinatal Hypoxic Conditions: HIF and Other Hypoxic Markers
por: Berna-Erro, Alejandro, et al.
Publicado: (2023)

HIF-1-Dependent Induction of Jumonji Domain-Containing Protein (JMJD) 3 under Hypoxic Conditions
por: Lee, Ho-Youl, et al.
Publicado: (2014)

HIF1α/HIF2α induces glioma cell dedifferentiation into cancer stem cells through Sox2 under hypoxic conditions
por: Wang, Pan, et al.
Publicado: (2022)

YAP nuclear translocation induced by HIF-1α prevents DNA damage under hypoxic conditions
por: Chang, Heng-Ai, et al.
Publicado: (2023)

Inhibition of SIRT1 Impairs the Accumulation and Transcriptional Activity of HIF-1α Protein under Hypoxic Conditions
por: Laemmle, Alexander, et al.
Publicado: (2012)

HIF-2α-ILK Is Involved in Mesenchymal Stromal Cell Angiogenesis in Multiple Myeloma Under Hypoxic Conditions
por: Zhang, Xiaoying, et al.
Publicado: (2018)

Overexpression of CD44 Standard Isoform Upregulates HIF-1α Signaling in Hypoxic Breast Cancer Cells
por: Ryu, Dayoung, et al.
Publicado: (2018)

Overexpression of Neutrophil MMP-9 and HIF-1α May Contribute to the Finger-Like Projections Formation and Histo-Pathogenesis in Nasal Inverted Papilloma
por: Li, Tao, et al.
Publicado: (2021)

Influence of Dll4 via HIF-1α-VEGF Signaling on the Angiogenesis of Choroidal Neovascularization under Hypoxic Conditions
por: Dong, Xiao, et al.
Publicado: (2011)

HVEM/HIF-1α promoted proliferation and inhibited apoptosis of ovarian cancer cells under hypoxic microenvironment conditions
por: Duan, Liyan, et al.
Publicado: (2020)

MMP-9 overexpression is associated with intragenic hypermethylation of MMP9 gene in melanoma
por: Falzone, Luca, et al.
Publicado: (2016)

The HIF1α/HIF2α-miR210-3p network regulates glioblastoma cell proliferation, dedifferentiation and chemoresistance through EGF under hypoxic conditions
por: Wang, Pan, et al.
Publicado: (2020)

The Apoptotic Effect of HIF-1α Inhibition Combined with Glucose plus Insulin Treatment on Gastric Cancer under Hypoxic Conditions
por: Tanaka, Tomokazu, et al.
Publicado: (2015)

HIF-1α affects trophoblastic apoptosis involved in the onset of preeclampsia by regulating FOXO3a under hypoxic conditions
por: Zhang, Zhan, et al.
Publicado: (2020)

UCA1 Overexpression Promotes Hypoxic Breast Cancer Cell Proliferation and Inhibits Apoptosis via HIF-1α Activation
por: Choudhry, Hani
Publicado: (2021)

Metformin increases PDH and suppresses HIF-1α under hypoxic conditions and induces cell death in oral squamous cell carcinoma
por: Guimarães, Talita Antunes, et al.
Publicado: (2016)

SIRT3 Regulates the ROS-FPR1/HIF-1α Axis under Hypoxic Conditions to Influence Lung Cancer Progression
por: Huang, Bo, et al.
Publicado: (2023)

JNK Contributes to Hif-1α Regulation in Hypoxic Neurons
por: Antoniou, Xanthi, et al.
Publicado: (2009)

Effects of the aqueous extract of a Tibetan herb, Rhodiola algida var. tangutica on proliferation and HIF-1α, HIF-2α expression in MCF-7 cells under hypoxic condition in vitro
por: Qi, Yu-juan, et al.
Publicado: (2015)

Distinct breast cancer stem/progenitor cell populations require either HIF1α or loss of PHD3 to expand under hypoxic conditions
por: Iriondo, Oihana, et al.
Publicado: (2015)

An interplay of microglia and matrix metalloproteinase MMP9 under hypoxic stress regulates the opticin expression in retina
por: Patnaik, Satish, et al.
Publicado: (2021)

Astrocyte HIF-2α supports learning in a passive avoidance paradigm under hypoxic stress
por: Leiton, Cindy V, et al.
Publicado: (2018)

Thymoquinone Selectively Kills Hypoxic Renal Cancer Cells by Suppressing HIF-1α-Mediated Glycolysis
por: Lee, Yoon-Mi, et al.
Publicado: (2019)

γ-H2AX promotes hepatocellular carcinoma angiogenesis via EGFR/HIF-1α/VEGF pathways under hypoxic condition
por: Xiao, Heng, et al.
Publicado: (2014)

Expression and significance of MMP2 and HIF-1α in hepatocellular carcinoma
por: WANG, BIN, et al.
Publicado: (2014)

Association of NRF2 with HIF-2α-induced cancer stem cell phenotypes in chronic hypoxic condition
por: Hallis, Steffanus Pranoto, et al.
Publicado: (2023)

IL-33-HIF1α Axis in Hypoxic Pulmonary Hypertension
por: Kumar, Rahul, et al.
Publicado: (2018)

p21(WAF1/Cip1) Regulation by hYSK1 Activates SP-1 Transcription Factor and Increases MMP-2 Expression under Hypoxic Conditions
por: Lee, Mee-Hyun, et al.
Publicado: (2019)

Nuclear Factor-κB–Dependent Epithelial to Mesenchymal Transition Induced by HIF-1α Activation in Pancreatic Cancer Cells under Hypoxic Conditions
por: Cheng, Zhuo-Xin, et al.
Publicado: (2011)

HIF2α-Sp1 interaction mediates a deacetylation-dependent FVII-gene activation under hypoxic conditions in ovarian cancer cells
por: Koizume, Shiro, et al.
Publicado: (2012)

Digoxin Downregulates NDRG1 and VEGF through the Inhibition of HIF-1α under Hypoxic Conditions in Human Lung Adenocarcinoma A549 Cells
por: Wei, Dong, et al.
Publicado: (2013)

Maslinic Acid Induces Mitochondrial Apoptosis and Suppresses HIF-1α Expression in A549 Lung Cancer Cells under Normoxic and Hypoxic Conditions
por: Hsia, Te-Chun, et al.
Publicado: (2014)

MicroRNA-519d-3p Inhibits Proliferation and Promotes Apoptosis by Targeting HIF-2α in Cervical Cancer Under Hypoxic Conditions
por: Jiang, Lixia, et al.
Publicado: (2018)

DYRK1A suppression attenuates HIF-1α accumulation and enhances the anti-liver cancer effects of regorafenib and sorafenib under hypoxic conditions
por: Zhang, Chong, et al.
Publicado: (2022)

Experimental Study on the Correlation between miRNA-373 and HIF-1α, MMP-9, and VEGF in the Development of HIE
por: Liu, Chun-Yang, et al.
Publicado: (2021)

A Chinese Herbal Formula Suppresses Colorectal Cancer Migration and Vasculogenic Mimicry Through ROS/HIF-1α/MMP2 Pathway in Hypoxic Microenvironment
por: Zong, Shaoqi, et al.
Publicado: (2020)

Yes-associated protein (YAP) binds to HIF-1α and sustains HIF-1α protein stability to promote hepatocellular carcinoma cell glycolysis under hypoxic stress
por: Zhang, Xiaodong, et al.
Publicado: (2018)

HIF2α/EFEMP1 cascade mediates hypoxic effects on breast cancer stem cell hierarchy
por: Kwak, Ji-Hye, et al.
Publicado: (2016)

MMP-7 and MMP-9 are overexpressed in the synovial tissue from severe temporomandibular joint dysfunction
por: Loreto, Carla, et al.
Publicado: (2020)

Acriflavine, a Potent Inhibitor of HIF-1α, Disturbs Glucose Metabolism and Suppresses ATF4-Protective Pathways in Melanoma under Non-hypoxic Conditions
por: Martí-Díaz, Román, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_m1a72j1he2hf4kjo9oc5662b1e